Cupa UEFA 1980-1981 a fost căștigată de Ipswich Town cu 5 la 4, la general, în fața clubului olandez, AZ Alkmaar.
Runda I
Tur
Retur
Juventus won 6–4 on aggregate.
Widzew Łódź 1–1 Manchester United on aggregate. Widzew Łódź advanced on away goals rule.
Torino won 4–3 on aggregate.
Runda a II-a
Tur
Retur
Torino won 3–2 on aggregate.
Juventus 4–4 Widzew Łódź on aggregate. Widzew Łódź won 4–1 on penalties.
Runda a III-a
Tur
Retur
Torino 3–3 Grasshoppers on aggregate. Grasshoppers won 4–3 on penalties.
Sferuri
Tur
Retur
Semifinalele
Retur
Finala
Legături externe Official Site Results at RSSSF.com
Categorie:Sezoanele Cupei UEFA Uefa Cup, 1980–81 Uefa Cup, 1980–81