Melissa Leo (født 1960) er en amerikansk skuespiller.
Leo ble kjent gjennom sin rolle i Homicide: Drapsavsnittet mellom 1993 og 1997. Hun har hatt flere TV-roller i andre serier, og også flere biroller i filmer. I 2008 hadde hun en av hovedrollene i dramafilmen Frozen River, en rolle hun ble Oscar-nominert for.
Under Oscar 2011 vant hun Oscar for beste kvinnelige birolle for rollen som Alice Ward i The Fighter. For denne rollen vant hun også Golden Globe i samme kategori.
Leo spilte i TV-serien Treme.
Filmografi thumb|Christian Bale, Natalie Portman, Leo og Colin Firth med prisene sine under den 83. Oscar-utdelingen i 2011. YearTittelRolle Merknad 1984 All My Children Linda Warner 1985 Always Peggy 1985 Streetwalkin''' | Cookie
| 1985 | Silent Witness| Patti Mullen | TV movie |- | 1986 | Deadtime Stories| Judith «MaMa» Baer
| 1988 | | Josie Larraneta
| 1989 | The Young Riders| Emma Shannon
| 1989 | Nasty Boys| Katie Morrisey | TV |- | 1990 | The Bride in Black| Mary Margaret | TV |- | 1991 | Carolina Skeletons| Cassie | TV |- | 1992 | Immaculate ConceptionFilm hos IMDb | Hannah
| 1992 |Venice/Venice| Peggy
| 1993 | | Beatrice Grey
| 1993 | Homicide: Life on the Street| Det. Sgt. Kay Howard
| 1994 | Garden| Elizabeth
| 1995 | Last Summer in the Hamptons| Trish
| 1995 | In the Line of Duty: Hunt for Justice| Carol Manning | TV |- | 1997 | Under the Bridge| Kathy
| 1999 | The 24 Hour Woman| Dr. Suzanne Pincus
| 1999 | Code of Ethics| Jo DeAngelo
| 2000 | Homicide: The Movie| Det. Sgt. Kay Howard | TV |- | 2000 | Fear of Fiction| Sigrid Anderssen
| 2003 | 21 Grams| Marianne Jordan
| 2004 | First Breath| Detective Waxman
| 2004 | From Other Worlds| Miriam
| 2005 | Hide and Seek| Laura
| 2005 | Runaway| Lisa Adler
| 2005 | No Shoulder| Ruth
| 2005 | Patch| Maelynn
| 2005 | | Rachel
| 2005 | American Gun| Louise
| 2005 | Confess| Agnes Lessor
| 2006 | Stephanie Daley| Miri
| 2006 | The Limbo Room| KC Collins
| 2006 | Hollywood Dreams| Aunt Bee
| 2006 | | Mrs. Miller
| 2006 | Falling Objects| Helga
| 2007 | Bomb| Sharon
| 2007 | Midnight Son| Rita
| 2007 | Black Irish| Margaret McKay
| 2007 | | Ceci
| 2007 | Racing Daylight| Sadie Stokes/Anna Stokes
| 2007 | I Believe in America| Soto
| 2007 | Mr. Woodcock| Sally Jansen
| 2007 | One Night| Wendy
| 2008 | Frozen River| Ray Eddy
| 2008 | | Kathy Walsh
| 2008 | Lullaby| Stephanie
| 2008 | Night of the Living JewsNight of the Living Jews – Credits . | Zombie
| 2008 | Santa Mesa| Maggie
| 2008 | Ball Don't Lie| Georgia
| 2008 | This is a Story About Ted and Alice| Alice
| 2008 | Righteous Kill| Cheryl Brooks
| 2008 | Why Stop Now| Penny
| 2009 | According to Greta| Karen
| 2009 | Stephanie's Image| Stephanie
| 2009 | True Adolescents| Sharon
| 2009 | Veronika Decides to Die| Mari
| 2009 | Dear Lemon Lima| Mrs. Howard
| 2009 | Don McKay| Marie
| 2009 | Everybody's Fine| Colleen
| 2010 | Treme| Toni Bernette
| 2010 | Welcome to the Rileys| Mrs. Lois Riley
| 2010 | | Martha
| 2010 | The Space Between| Montine
| 2010 | | Alice Ward
| 2010 | Conviction| Nancy Taylor
| 2011 | Red State Sarah Cooper 2011 The Sea Is All I Know Sara 2012 Flight Ellen Block 2012 Why Stop Now Penny Bloom 2013 Olympus Has Fallen Ruth McMillan 2013 Oblivion Sally 2013 Lee Daniels' The Butler Mamie Eisenhower Scenes deleted 2013 Prisoners Holly Jones 2013 Call Me Crazy: A Five Film Robin 2013 Charlie Countryman Charlies mor 2014 The Angriest Man in Brooklyn Bette Altmann 2014 The EqualizerSusan Plummer 2014 I Fought the Law Alice McMillan 2015 London Has Fallen Ruth McMillan 2016 Snowden Laura Poitras
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Kategori:Skuespillere fra USA Kategori:Oscar-vinnere (birolle) Kategori:Emmy-vinnere Kategori:Personer fra New York City