テアフラビン-3-ガラート（）は、テアフラビン誘導体の一つで、没食子酸エステルである。
紅茶に豊富に含まれ、発酵により生成するX. Hu, Z. Ping, M. Gan et al., “Theaflavin-3,3′-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway,” Acta Biomaterialia 48 (2017): 479–488.Shan Z, Nisar M, Li M, Zhang C, Wan C. Theaflavin Chemistry and Its Health Benefits Oxidative Medicine and Cellular Longevity. 2021 Jan;2021. .。シスプラチンと組み合わせることで卵巣癌細胞に対する抗がん剤として研究されているShan Z, Nisar M, Li M, Zhang C, Wan C. Theaflavin Chemistry and Its Health Benefits Oxidative Medicine and Cellular Longevity. 2021 Jan;2021..Y. Gao, J. Yin, Y. Tu, and Y. Chen, “Theaflavin-3, 3′-digallate suppresses human ovarian carcinoma OVCAR-3 cells by regulating the checkpoint kinase 2 and p27 kip1 pathways,” Molecules 24 (4): 673, 2019H. Pan, E. Kim, G. Rankin, Y. Rojanasakul, Y. Tu, and Y. Chen, “Theaflavin-3, 3′-Digallate enhances the inhibitory effect of cisplatin by regulating the copper transporter 1 and glutathione in human ovarian cancer cells,” International Journal of Molecular Sciences 19 (1): 117, 2018.。紅茶の大量摂取による、女性の老化の抑制効果が報告されているShan Z, Nisar M, Li M, Zhang C, Wan C., "Theaflavin Chemistry and Its Health Benefits", Oxidative Medicine and Cellular Longevity 2021 Jan; 2021. .Y. Oka, S. Iwai, H. Amano et al., “Tea polyphenols inhibit rat osteoclast formation and differentiation,” Journal of Pharmacological Sciences 118 (1): 55–64, 2012.。
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