Arcade Fire, Chris Brown, Muse, Miranda Lambert, John Mayer, Beyoncé i Alicia Keys po trzy nominacje, zaś Robert Plant, Pink, Justin Bieber, Mumford & Sons, Monica, La Roux, Goldfrapp, Janelle Monáe, Sade, Michael Bublé, Fantasia, Hayley Williams, The White Stripes i obsada serialu Glee zdobyli po dwie nominacje.
Występujący Pre-telecast ChocQuibTown Trombone Shorty Buddy Guy, Cyndi Lauper, Maria Muldaur, Kenny Wayne Shepherd, Mavis Staples & Betty Wright Kirk Whalum
Telecast ArtystaPiosenkaYolanda AdamsChristina AguileraJennifer HudsonMartina McBrideFlorence WelchHołd wobec Arethy Franklin:„(You Make Me Feel Like) A Natural Woman”„Ain’t No Way” (Aguilera)„Until You Come Back to Me (That’s What I’m Gonna Do)” (McBride)„Think” (Welch)„Respect” (Hudson)„Spirit in the Dark” (Adams)„Sisters Are Doin’ It for Themselves”Lady Gaga„Born This Way”Miranda Lambert„The House That Built Me”Muse„Uprising”B.o.BBruno MarsJanelle Monáe„Nothin’ on You”„Grenade”„Cold War”Justin BieberJaden Smith„Baby”„Never Say Never” Usher„OMG”Mumford & SonsThe Avett BrothersBob Dylan„The Cave”„Head Full of Doubt”„Maggie’s Farm”Lady Antebellum„If You Don’t Know Me By Now”„American Honey”„Need You Now”Cee-Lo GreenGwyneth PaltrowThe Muppets„Forget You”Katy Perry„Not Like the Movies”„Teenage Dream”Norah JonesJohn MayerKeith Urban„Jolene”EminemAdam