Najlepszy żeński teledysk Taylor Swift – "You Belong With Me" Beyoncé – "Single Ladies (Put a Ring on It)" Katy Perry – "Hot N Cold" Kelly Clarkson – "My Life Would Suck Without You" Lady GaGa – "Poker Face" Pink – "So What"
Najlepszy męski teledysk Eminem – "We Made You" Jay-Z – "D.O.A. (Death of Auto-Tune)" Kanye West – "Love Lockdown" Ne-Yo – "Miss Independent" T.I. feat. Rihanna – "Live Your Life"
Najlepszy teledysk hip hopowy Asher Roth – "I Love College" Eminem – "We Made You" Flo Rida – "Right Round" Jay-Z – "D.O.A. (Death of Auto-Tune)" Kanye West – "Love Lockdown"
Najlepszy teledysk popowy Beyoncé – "Single Ladies (Put a Ring on It)" Britney Spears – "Womanizer" Cobra Starship feat. Leighton Meester – "Good Girls Go Bad" Lady GaGa – "Poker Face" Wisin y Yandel – "Abusadora"
Najlepszy teledysk rockowy Coldplay – "Viva la Vida" Fall Out Boy – "I Don’t Care" Green Day – "21 Guns" Kings of Leon – "Use Somebody" Paramore – "Decode"
Najlepszy nowy artysta 3OH!3 – "Don't Trust Me" Asher Roth – "I Love College" Drake – "Best I Ever Had" Kid Cudi – "Day N' Nite" Lady GaGa – "Poker Face"