Nagrody ogólne Nagranie Roku "Irreaplaceable" Beyoncé Knowles (producenci: Jim Caruana, Jason Goldstein & Geoff Rice) "The Pretender" Foo Fighters (producenci: Adrian Bushby & Rich Costey) "What Goes Around...Comes Around" Justin Timberlake (producenci: Jimmy Douglass & Timbaland) "Rehab" Amy Winehouse (producent: Tom Elmhirst)
Album Roku "Echoes, Silence, Patience & Grace" Foo Fighters "These Days" Vince Gill "River: The Joni Letters" Herbie Hancock "Graduation" Kanye West " Back To Black" Amy Winehouse
Piosenka Roku "Before He Cheats" Carrie Underwood "Hey There Delilah" Plain White T’s "Like A Star" Corinne Bailey Rae "Rehab" Amy Winehouse "Umbrella" Rihanna z Jay-Z
Najlepszy Nowy Artysta Feist Ledisi Paramore Taylor Swift Amy Winehouse Pop Najlepsze Żeńskie Wykonanie Pop "Candyman" Christina Aguilera "1234" Feist "Big Girls Don’t Cry" Fergie "Say It Right" Nelly Furtado "Rehab" Amy Winehouse Najlepsze Męskie Wykonanie Pop "Everything" Michael Bublé "Belief" John Mayer "Dance Tonight" Paul McCartney "Amazing" Seal "What Goes Around...Comes Around" Justin Timberlake Najlepsze Wokalne Wykonanie przez Duet lub Grupę "(You Want To) Make A Memory" Bon Jovi "Home" Daughtry "Makes Me Wonder" Maroon 5 "Hey There Delilah" Plain White T’s "Window In The Skies" U2