Amy Winehouse – "Rehab", "You Know I'm No Good" Carrie Underwood – "Before He Cheats" Gym Class Heroes ft Patrick Stump – "Clothes Off", "Cupid’s Chokehold/Breakfast in America" Lily Allen – "Alfie", "Smile", "LDN" Peter Bjorn and John – "Young Folks"
Najlepszy zespół
Fall Out Boy – "This Ain’t a Scene, It’s an Arms Race", "Thnks Fr Th Mmrs" Gym Class Heroes ft Patrick Stump – "Clothes Off", "Cupid’s Chokehold/Breakfast in America" Linkin Park – "What I've Done" Maroon 5 – "Makes Me Wonder" White Stripes – "Icky Thump"
Most Earthshattering Collaboration
Akon ft Eminem – "Smack That" Beyoncé ft Shakira – "Beautiful Liar" Justin Timberlake ft Timbaland – "SexyBack" Gwen Stefani ft Akon – "The Sweet Escape" U2 ft Green Day – "The Saints Are Coming"
Quadruple Threat of the Year
Beyoncé Bono Jay-Z Justin Timberlake Kanye West
Najlepszy singel roku
Avril Lavigne – "Girlfriend" Daughtry – "Home" Fall Out Boy – "Thnks Fr Th Mmrs" Lil Mama – "Lip Gloss (No Music)" T-Pain ft Yung Joc – "Buy U a Drank (Shawty Snappin')" Timbaland ft Keri Hilson, D.O.E.